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In some cases, temporary dose reduction, switching to an alternative GLP-1 preparation, or clinician-supervised, short-term anti-emetic medication may be appropriate

This change to the structure extends the half-life to about 170 to 180 hours, which allows for dosing once a week

On the other hand, if you're taking cyanocobalamin, know that: Cyanocobalamin injections are generally given every day during the first week of your treatment